Small molecule annotation for the Protein Data Bank
نویسندگان
چکیده
منابع مشابه
Small molecule annotation for the Protein Data Bank
The Protein Data Bank (PDB) is the single global repository for three-dimensional structures of biological macromolecules and their complexes, and its more than 100,000 structures contain more than 20,000 distinct ligands or small molecules bound to proteins and nucleic acids. Information about these small molecules and their interactions with proteins and nucleic acids is crucial for our under...
متن کاملChemical annotation of small and peptide-like molecules at the Protein Data Bank
Over the past decade, the number of polymers and their complexes with small molecules in the Protein Data Bank archive (PDB) has continued to increase significantly. To support scientific advancements and ensure the best quality and completeness of the data files over the next 10 years and beyond, the Worldwide PDB partnership that manages the PDB archive is developing a new deposition and anno...
متن کاملThe Protein Data Bank
The Protein Data Bank [PDB; Berman, Westbrook et al. (2000), Nucleic Acids Res. 28, 235-242; http://www.pdb.org/] is the single worldwide archive of primary structural data of biological macromolecules. Many secondary sources of information are derived from PDB data. It is the starting point for studies in structural bioinformatics. This article describes the goals of the PDB, the systems in pl...
متن کاملA Biocurator Perspective: Annotation at the Research Collaboratory for Structural Bioinformatics Protein Data Bank
L ike most scientists, annotators at the Research Collaboratory for Structural Bioinformatics (RCSB) (http://www.pdb.org) dread the immortal cocktail party question ‘‘So, what do you do?’’ Unlike for some jobs, however, their answer can leave other scientists at the party with no response. Even within the structural biology community, our job is not well-understood. Throughout this perspective,...
متن کاملPDBWiki: added value through community annotation of the Protein Data Bank
The success of community projects such as Wikipedia has recently prompted a discussion about the applicability of such tools in the life sciences. Currently, there are several such 'science-wikis' that aim to collect specialist knowledge from the community into centralized resources. However, there is no consensus about how to achieve this goal. For example, it is not clear how to best integrat...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Database
سال: 2014
ISSN: 1758-0463
DOI: 10.1093/database/bau116